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Desferrithiocin: A Search for Clinically Effective Iron Chelators
[Image: see text] The successful search for orally active iron chelators to treat transfusional iron-overload diseases, e.g., thalassemia, is overviewed. The critical role of iron in nature as a redox engine is first described, as well as how primitive life forms and humans manage the metal. The pro...
Autores principales: | Bergeron, Raymond J., Wiegand, Jan, McManis, James S., Bharti, Neelam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255733/ https://www.ncbi.nlm.nih.gov/pubmed/25207964 http://dx.doi.org/10.1021/jm500828f |
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