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Cyclodextrin Complexes of Reduced Bromonoscapine in Guar Gum Microspheres Enhance Colonic Drug Delivery

[Image: see text] Here, we report improved solubility and enhanced colonic delivery of reduced bromonoscapine (Red-Br-Nos), a cyclic ether brominated analogue of noscapine, upon encapsulation of its cyclodextrin (CD) complexes in bioresponsive guar gum microspheres (GGM). Phase–solubility analysis s...

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Detalles Bibliográficos
Autores principales:	Madan, Jitender, Gundala, Sushma R., Baruah, Bharat, Nagaraju, Mulpuri, Yates, Clayton, Turner, Timothy, Rangari, Vijay, Hamelberg, Donald, Reid, Michelle D., Aneja, Ritu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255741/ https://www.ncbi.nlm.nih.gov/pubmed/25350222 http://dx.doi.org/10.1021/mp500408n

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