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Transcriptional and epigenetic regulation of T-helper lineage specification

Combined with TCR stimuli, extracellular cytokine signals initiate the differentiation of naive CD4(+) T cells into specialized effector T-helper (Th) and regulatory T (Treg) cell subsets. The lineage specification and commitment process occurs through the combinatorial action of multiple transcript...

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Detalles Bibliográficos
Autores principales:	Tripathi, Subhash K, Lahesmaa, Riitta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Invited Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255756/ https://www.ncbi.nlm.nih.gov/pubmed/25123277 http://dx.doi.org/10.1111/imr.12204

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