Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha‐synuclein in oligodendrocytes

Mice overexpressing human alpha‐synuclein in oligodendrocytes (MBP1‐α‐syn) recapitulate some key functional and neuropathological features of multiple system atrophy (MSA). Whether or not these mice develop severe autonomic failure, which is a key feature of human MSA, remains unknown. We explored c...

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Detalles Bibliográficos
Autores principales: Tank, Jens, da Costa‐Goncalves, Andrey C., Kamer, Ilona, Qadri, Fatimunnisa, Ubhi, Kiren, Rockenstein, Edward, Diedrich, André, Masliah, Eliezer, Gross, Volkmar, Jordan, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255815/
https://www.ncbi.nlm.nih.gov/pubmed/25428949
http://dx.doi.org/10.14814/phy2.12209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255815/
https://www.ncbi.nlm.nih.gov/pubmed/25428949
http://dx.doi.org/10.14814/phy2.12209

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