A putative role for homocysteine in the pathophysiology of acute bacterial meningitis in children

BACKGROUND: Acute bacterial meningitis frequently causes cortical and hippocampal neuron loss leading to permanent neurological sequelae. Neuron death in acute bacterial meningitis involves the excessive activation of NMDA receptors and p53-mediated apoptosis, and the latter is triggered by the depl...

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Detalles Bibliográficos
Autores principales: Coimbra, Roney Santos, Calegare, Bruno Frederico Aguilar, Candiani, Talitah Michel Sanchez, D’Almeida, Vânia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255930/
https://www.ncbi.nlm.nih.gov/pubmed/25477764
http://dx.doi.org/10.1186/1472-6890-14-43

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