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Castleman’s disease- a diagnostic dilemma
Castleman’s disease is a benign lymphoproliferative disease characterised by hyperplasia of lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian patient who presented with six months history of shortness of breath with CT scan confirming an 8 cm segment of cons...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255971/ https://www.ncbi.nlm.nih.gov/pubmed/25431102 http://dx.doi.org/10.1186/s13019-014-0170-0 |
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author | Barua, Anupama Vachlas, Kostas Milton, Richard Thorpe, James Andrew Charles |
author_facet | Barua, Anupama Vachlas, Kostas Milton, Richard Thorpe, James Andrew Charles |
author_sort | Barua, Anupama |
collection | PubMed |
description | Castleman’s disease is a benign lymphoproliferative disease characterised by hyperplasia of lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian patient who presented with six months history of shortness of breath with CT scan confirming an 8 cm segment of consolidated lung in left hilum. PET scan revealed a mass measuring 68x80x55 mm extending from the left hilum out into the left upper lobe containing area of calcification with SUV max 4.8. The differential diagnosis included atypical sequestration, hamartoma and primary lung malignancy. The patient underwent left video assisted enucleation of the lesion. The histology confirmed the diagnosis of Castleman’s disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13019-014-0170-0) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4255971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42559712014-12-05 Castleman’s disease- a diagnostic dilemma Barua, Anupama Vachlas, Kostas Milton, Richard Thorpe, James Andrew Charles J Cardiothorac Surg Case Report Castleman’s disease is a benign lymphoproliferative disease characterised by hyperplasia of lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian patient who presented with six months history of shortness of breath with CT scan confirming an 8 cm segment of consolidated lung in left hilum. PET scan revealed a mass measuring 68x80x55 mm extending from the left hilum out into the left upper lobe containing area of calcification with SUV max 4.8. The differential diagnosis included atypical sequestration, hamartoma and primary lung malignancy. The patient underwent left video assisted enucleation of the lesion. The histology confirmed the diagnosis of Castleman’s disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13019-014-0170-0) contains supplementary material, which is available to authorized users. BioMed Central 2014-11-28 /pmc/articles/PMC4255971/ /pubmed/25431102 http://dx.doi.org/10.1186/s13019-014-0170-0 Text en © Barua et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Barua, Anupama Vachlas, Kostas Milton, Richard Thorpe, James Andrew Charles Castleman’s disease- a diagnostic dilemma |
title | Castleman’s disease- a diagnostic dilemma |
title_full | Castleman’s disease- a diagnostic dilemma |
title_fullStr | Castleman’s disease- a diagnostic dilemma |
title_full_unstemmed | Castleman’s disease- a diagnostic dilemma |
title_short | Castleman’s disease- a diagnostic dilemma |
title_sort | castleman’s disease- a diagnostic dilemma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255971/ https://www.ncbi.nlm.nih.gov/pubmed/25431102 http://dx.doi.org/10.1186/s13019-014-0170-0 |
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