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Castleman’s disease- a diagnostic dilemma

Castleman’s disease is a benign lymphoproliferative disease characterised by hyperplasia of lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian patient who presented with six months history of shortness of breath with CT scan confirming an 8 cm segment of cons...

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Detalles Bibliográficos
Autores principales: Barua, Anupama, Vachlas, Kostas, Milton, Richard, Thorpe, James Andrew Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255971/
https://www.ncbi.nlm.nih.gov/pubmed/25431102
http://dx.doi.org/10.1186/s13019-014-0170-0
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author Barua, Anupama
Vachlas, Kostas
Milton, Richard
Thorpe, James Andrew Charles
author_facet Barua, Anupama
Vachlas, Kostas
Milton, Richard
Thorpe, James Andrew Charles
author_sort Barua, Anupama
collection PubMed
description Castleman’s disease is a benign lymphoproliferative disease characterised by hyperplasia of lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian patient who presented with six months history of shortness of breath with CT scan confirming an 8 cm segment of consolidated lung in left hilum. PET scan revealed a mass measuring 68x80x55 mm extending from the left hilum out into the left upper lobe containing area of calcification with SUV max 4.8. The differential diagnosis included atypical sequestration, hamartoma and primary lung malignancy. The patient underwent left video assisted enucleation of the lesion. The histology confirmed the diagnosis of Castleman’s disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13019-014-0170-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-42559712014-12-05 Castleman’s disease- a diagnostic dilemma Barua, Anupama Vachlas, Kostas Milton, Richard Thorpe, James Andrew Charles J Cardiothorac Surg Case Report Castleman’s disease is a benign lymphoproliferative disease characterised by hyperplasia of lymphoid follicles. It can affect any lymph nodes in the body. Here we describe a caucasian patient who presented with six months history of shortness of breath with CT scan confirming an 8 cm segment of consolidated lung in left hilum. PET scan revealed a mass measuring 68x80x55 mm extending from the left hilum out into the left upper lobe containing area of calcification with SUV max 4.8. The differential diagnosis included atypical sequestration, hamartoma and primary lung malignancy. The patient underwent left video assisted enucleation of the lesion. The histology confirmed the diagnosis of Castleman’s disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13019-014-0170-0) contains supplementary material, which is available to authorized users. BioMed Central 2014-11-28 /pmc/articles/PMC4255971/ /pubmed/25431102 http://dx.doi.org/10.1186/s13019-014-0170-0 Text en © Barua et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Barua, Anupama
Vachlas, Kostas
Milton, Richard
Thorpe, James Andrew Charles
Castleman’s disease- a diagnostic dilemma
title Castleman’s disease- a diagnostic dilemma
title_full Castleman’s disease- a diagnostic dilemma
title_fullStr Castleman’s disease- a diagnostic dilemma
title_full_unstemmed Castleman’s disease- a diagnostic dilemma
title_short Castleman’s disease- a diagnostic dilemma
title_sort castleman’s disease- a diagnostic dilemma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255971/
https://www.ncbi.nlm.nih.gov/pubmed/25431102
http://dx.doi.org/10.1186/s13019-014-0170-0
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