Cargando…

Membrane Partitioning of Anionic, Ligand-Coated Nanoparticles Is Accompanied by Ligand Snorkeling, Local Disordering, and Cholesterol Depletion

Intracellular uptake of nanoparticles (NPs) may induce phase transitions, restructuring, stretching, or even complete disruption of the cell membrane. Therefore, NP cytotoxicity assessment requires a thorough understanding of the mechanisms by which these engineered nanostructures interact with the...

Descripción completa

Detalles Bibliográficos
Autores principales: Gkeka, Paraskevi, Angelikopoulos, Panagiotis, Sarkisov, Lev, Cournia, Zoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256007/
https://www.ncbi.nlm.nih.gov/pubmed/25474252
http://dx.doi.org/10.1371/journal.pcbi.1003917

Ejemplares similares