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Anti-tat Hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages

BACKGROUND: HIV-1 Tat is essential for HIV replication and is also a well-known neurotoxic factor causing HIV-associated neurocognitive disorder (HAND). Currently, combined antiretroviral therapy targeting HIV reverse transcriptase or protease cannot prevent the production of early viral proteins, e...

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Detalles Bibliográficos
Autores principales:	Kang, Wen, Marasco, Wayne A, Tong, Hsin-I, Byron, Mary Margaret, Wu, Chengxiang, Shi, Yingli, Sun, Si, Sun, Yongtao, Lu, Yuanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256057/ https://www.ncbi.nlm.nih.gov/pubmed/25416164 http://dx.doi.org/10.1186/s12974-014-0195-2

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