Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers

We previously used a single nucleotide polymorphism (SNP) in the CHRNA5-A3-B4 gene cluster associated with heaviness of smoking within smokers to confirm the causal effect of smoking in reducing body mass index (BMI) in a Mendelian randomisation analysis. While seeking to extend these findings in a...

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Detalles Bibliográficos
Autores principales: Taylor, Amy E., Morris, Richard W., Fluharty, Meg E., Bjorngaard, Johan H., Åsvold, Bjørn Olav, Gabrielsen, Maiken E., Campbell, Archie, Marioni, Riccardo, Kumari, Meena, Hällfors, Jenni, Männistö, Satu, Marques-Vidal, Pedro, Kaakinen, Marika, Cavadino, Alana, Postmus, Iris, Husemoen, Lise Lotte N., Skaaby, Tea, Ahluwalia, Tarunveer S., Treur, Jorien L., Willemsen, Gonneke, Dale, Caroline, Wannamethee, S. Goya, Lahti, Jari, Palotie, Aarno, Räikkönen, Katri, Kisialiou, Aliaksei, McConnachie, Alex, Padmanabhan, Sandosh, Wong, Andrew, Dalgård, Christine, Paternoster, Lavinia, Ben-Shlomo, Yoav, Tyrrell, Jessica, Horwood, John, Fergusson, David M., Kennedy, Martin A., Frayling, Tim, Nohr, Ellen A., Christiansen, Lene, Ohm Kyvik, Kirsten, Kuh, Diana, Watt, Graham, Eriksson, Johan, Whincup, Peter H., Vink, Jacqueline M., Boomsma, Dorret I., Davey Smith, George, Lawlor, Debbie, Linneberg, Allan, Ford, Ian, Jukema, J. Wouter, Power, Christine, Hyppönen, Elina, Jarvelin, Marjo-Riitta, Preisig, Martin, Borodulin, Katja, Kaprio, Jaakko, Kivimaki, Mika, Smith, Blair H., Hayward, Caroline, Romundstad, Pål R., Sørensen, Thorkild I. A., Munafò, Marcus R., Sattar, Naveed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256159/
https://www.ncbi.nlm.nih.gov/pubmed/25474695
http://dx.doi.org/10.1371/journal.pgen.1004799

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