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Evidence for Evolutionary and Nonevolutionary Forces Shaping the Distribution of Human Genetic Variants near Transcription Start Sites

The regions surrounding transcription start sites (TSSs) of genes play a critical role in the regulation of gene expression. At the same time, current evidence indicates that these regions are particularly stressed by transcription-related mutagenic phenomena. In this work we performed a genome-wide...

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Detalles Bibliográficos
Autores principales:	Scala, Giovanni, Affinito, Ornella, Miele, Gennaro, Monticelli, Antonella, Cocozza, Sergio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256220/ https://www.ncbi.nlm.nih.gov/pubmed/25474578 http://dx.doi.org/10.1371/journal.pone.0114432

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