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Genetic Analysis of the Cardiac Methylome at Single Nucleotide Resolution in a Model of Human Cardiovascular Disease
Epigenetic marks such as cytosine methylation are important determinants of cellular and whole-body phenotypes. However, the extent of, and reasons for inter-individual differences in cytosine methylation, and their association with phenotypic variation are poorly characterised. Here we present the...
Autores principales: | Johnson, Michelle D., Mueller, Michael, Adamowicz-Brice, Martyna, Collins, Melissa J., Gellert, Pascal, Maratou, Klio, Srivastava, Prashant K., Rotival, Maxime, Butt, Shahena, Game, Laurence, Atanur, Santosh S., Silver, Nicholas, Norsworthy, Penny J., Langley, Sarah R., Petretto, Enrico, Pravenec, Michal, Aitman, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256262/ https://www.ncbi.nlm.nih.gov/pubmed/25474312 http://dx.doi.org/10.1371/journal.pgen.1004813 |
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