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The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study
BACKGROUND: A possible increase in thyroid cancer in the young represents the most critical health problem to be considered after the nuclear accident in Fukushima, Japan (March 2011), which is an important lesson from the Chernobyl disaster (April 1986). Although it was reported that childhood thyr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256387/ https://www.ncbi.nlm.nih.gov/pubmed/25474311 http://dx.doi.org/10.1371/journal.pone.0113804 |
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author | Watanobe, Hajime Furutani, Tomoyuki Nihei, Masahiko Sakuma, Yu Yanai, Rie Takahashi, Miyuki Sato, Hideo Sagawa, Fumihiko |
author_facet | Watanobe, Hajime Furutani, Tomoyuki Nihei, Masahiko Sakuma, Yu Yanai, Rie Takahashi, Miyuki Sato, Hideo Sagawa, Fumihiko |
author_sort | Watanobe, Hajime |
collection | PubMed |
description | BACKGROUND: A possible increase in thyroid cancer in the young represents the most critical health problem to be considered after the nuclear accident in Fukushima, Japan (March 2011), which is an important lesson from the Chernobyl disaster (April 1986). Although it was reported that childhood thyroid cancer had started to increase 3–5 yr after the Chernobyl accident, we speculate that the actual period of latency might have been shorter than reported, considering the delay in initiating thyroid surveillance in the then Soviet Union and also the lower quality of ultrasonographic testing in the 1980s. Our primary objectives in the present study were to identify any possible thyroid abnormality in young Fukushima citizens at a relatively early timepoint (20–30 months) after the accident, and also to strive to find a possible relationship among thyroid ultrasonographic findings, thyroid-relevant biochemical markers, and iodine-131 ground deposition in the locations of residence where they stayed during very early days after the accident. METHODS AND FINDINGS: This is a cross-sectional study. We targeted the Fukushima residents who were 18 yr old or younger (including fetuses) at the time of the accident. Our examinations comprised a questionnaire, thyroid ultrasonography, thyroid-related blood tests, and urinary iodine measurement. We analyzed a possible relationship among thyroid ultrasonographic findings (1,137 subjects), serum hormonal data (731 subjects), urinary iodine concentrations (770 subjects), and iodine-131 ground deposition (1,137 subjects). We did not find any significant relationship among these indicators, and no participant was diagnosed to contract thyroid cancer. CONCLUSIONS: At the timepoint of 20–30 months after the accident, we did not confirm any discernible deleterious effects of the emitted radioactivity on the thyroid of young Fukushima residents. This is the first report in English detailing the thyroid status of young Fukushima residents after the nuclear disaster. |
format | Online Article Text |
id | pubmed-4256387 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-42563872014-12-11 The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study Watanobe, Hajime Furutani, Tomoyuki Nihei, Masahiko Sakuma, Yu Yanai, Rie Takahashi, Miyuki Sato, Hideo Sagawa, Fumihiko PLoS One Research Article BACKGROUND: A possible increase in thyroid cancer in the young represents the most critical health problem to be considered after the nuclear accident in Fukushima, Japan (March 2011), which is an important lesson from the Chernobyl disaster (April 1986). Although it was reported that childhood thyroid cancer had started to increase 3–5 yr after the Chernobyl accident, we speculate that the actual period of latency might have been shorter than reported, considering the delay in initiating thyroid surveillance in the then Soviet Union and also the lower quality of ultrasonographic testing in the 1980s. Our primary objectives in the present study were to identify any possible thyroid abnormality in young Fukushima citizens at a relatively early timepoint (20–30 months) after the accident, and also to strive to find a possible relationship among thyroid ultrasonographic findings, thyroid-relevant biochemical markers, and iodine-131 ground deposition in the locations of residence where they stayed during very early days after the accident. METHODS AND FINDINGS: This is a cross-sectional study. We targeted the Fukushima residents who were 18 yr old or younger (including fetuses) at the time of the accident. Our examinations comprised a questionnaire, thyroid ultrasonography, thyroid-related blood tests, and urinary iodine measurement. We analyzed a possible relationship among thyroid ultrasonographic findings (1,137 subjects), serum hormonal data (731 subjects), urinary iodine concentrations (770 subjects), and iodine-131 ground deposition (1,137 subjects). We did not find any significant relationship among these indicators, and no participant was diagnosed to contract thyroid cancer. CONCLUSIONS: At the timepoint of 20–30 months after the accident, we did not confirm any discernible deleterious effects of the emitted radioactivity on the thyroid of young Fukushima residents. This is the first report in English detailing the thyroid status of young Fukushima residents after the nuclear disaster. Public Library of Science 2014-12-04 /pmc/articles/PMC4256387/ /pubmed/25474311 http://dx.doi.org/10.1371/journal.pone.0113804 Text en © 2014 Watanobe et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Watanobe, Hajime Furutani, Tomoyuki Nihei, Masahiko Sakuma, Yu Yanai, Rie Takahashi, Miyuki Sato, Hideo Sagawa, Fumihiko The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study |
title | The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study |
title_full | The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study |
title_fullStr | The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study |
title_full_unstemmed | The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study |
title_short | The Thyroid Status of Children and Adolescents in Fukushima Prefecture Examined during 20–30 Months after the Fukushima Nuclear Power Plant Disaster: A Cross-Sectional, Observational Study |
title_sort | thyroid status of children and adolescents in fukushima prefecture examined during 20–30 months after the fukushima nuclear power plant disaster: a cross-sectional, observational study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256387/ https://www.ncbi.nlm.nih.gov/pubmed/25474311 http://dx.doi.org/10.1371/journal.pone.0113804 |
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