Rapid Profiling of the Antigen Regions Recognized by Serum Antibodies Using Massively Parallel Sequencing of Antigen-Specific Libraries

There is a need for techniques capable of identifying the antigenic epitopes targeted by polyclonal antibody responses during deliberate or natural immunization. Although successful, traditional phage library screening is laborious and can map only some of the epitopes. To accelerate and improve epi...

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Detalles Bibliográficos
Autores principales: Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, D'Aliberti, Deborah, Venza, Mario, Borgogni, Erica, Castellino, Flora, Biondo, Carmelo, D'Andrea, Daniel, Grassi, Luigi, Tramontano, Anna, Teti, Giuseppe, Felici, Franco, Beninati, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256389/
https://www.ncbi.nlm.nih.gov/pubmed/25473968
http://dx.doi.org/10.1371/journal.pone.0114159

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