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Interleukin-1 and Interferon-γ Orchestrate β-Glucan-Activated Human Dendritic Cell Programming via IκB-ζ Modulation
Recognition of microbial components via innate receptors including the C-type lectin receptor Dectin-1, together with the inflammatory environment, programs dendritic cells (DCs) to orchestrate the magnitude and type of adaptive immune responses. The exposure to β-glucan, a known Dectin-1 agonist an...
Autores principales: | Cardone, Marco, Dzutsev, Amiran K., Li, Hongchuan, Riteau, Nicolas, Gerosa, Franca, Shenderov, Kevin, Winkler-Pickett, Robin, Provezza, Lisa, Riboldi, Elena, Leighty, Robert M., Orr, Selinda J., Steinhagen, Folkert, Wewers, Mark D., Sher, Alan, Anderson, Stephen K., Goldszmid, Romina, McVicar, Daniel W., Lyakh, Lyudmila, Trinchieri, Giorgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256441/ https://www.ncbi.nlm.nih.gov/pubmed/25474109 http://dx.doi.org/10.1371/journal.pone.0114516 |
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