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Aminoglycoside Stress Together with the 12S rRNA 1494C>T Mutation Leads to Mitophagy

Aminoglycosides as modifying factors modulated the phenotypic manifestation of mitochondrial rRNA mutations and the incomplete penetrance of hearing loss. In this report, using cybrids harboring the m.1494C>T mutation, we showed that gentamycin aggravated mitochondrial dysfunction in a combinatio...

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Detalles Bibliográficos
Autores principales:	Yu, Jialing, Zheng, Jing, Zhao, Xiaoxu, Liu, Junxia, Mao, Zhuochao, Ling, Yining, Chen, Danni, Chen, Chao, Hui, Lanlan, Cui, Limei, Chen, Ye, Jiang, Pingping, Guan, Min-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256443/ https://www.ncbi.nlm.nih.gov/pubmed/25474306 http://dx.doi.org/10.1371/journal.pone.0114650

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