Cargando…

Anti-Inflammatory Effects of Secondary Metabolites of Marine Pseudomonas sp. in Human Neutrophils Are through Inhibiting P38 MAPK, JNK, and Calcium Pathways

Activated neutrophils play a significant role in the pathogenesis of many inflammatory diseases. The metabolites of marine microorganisms are increasingly employed as sources for developing new drugs; however, very few marine drugs have been studied in human neutrophils. Herein, we showed that secon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Shun-Chin, Sung, Ping-Jyun, Lin, Chwan-Fwu, Kuo, Jimmy, Chen, Chun-Yu, Hwang, Tsong-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256452/ https://www.ncbi.nlm.nih.gov/pubmed/25474595 http://dx.doi.org/10.1371/journal.pone.0114761

Ejemplares similares

Bioactive Secondary Metabolites of a Marine Bacillus sp. Inhibit Superoxide Generation and Elastase Release in Human Neutrophils by Blocking Formyl Peptide Receptor 1
por: Yang, Shun-Chin, et al.
Publicado: (2013)

Nor-24-homoscalaranes, Neutrophilic Inflammatory Mediators from the Marine Sponge Lendenfeldia sp.
por: Peng, Bo-Rong, et al.
Publicado: (2023)

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma
por: Pua, Lesley Jia Wei, et al.
Publicado: (2022)

Scalarane-Type Sesterterpenoids from the Marine Sponge Lendenfeldia sp. Alleviate Inflammation in Human Neutrophils
por: Peng, Bo-Rong, et al.
Publicado: (2021)

Anti-inflammatory effects of Perilla frutescens in activated human neutrophils through two independent pathways: Src family kinases and Calcium
por: Chen, Chun-Yu, et al.
Publicado: (2015)

New Marine Sterols from a Gorgonian Pinnigorgia sp.
por: Chang, Yu-Chia, et al.
Publicado: (2017)

Cationic additives in nanosystems activate cytotoxicity and inflammatory response of human neutrophils: lipid nanoparticles versus polymeric nanoparticles
por: Hwang, Tsong-Long, et al.
Publicado: (2015)

Data on the phosphorylation of p38MAPK and JNK induced by chlorpyrifos in Drosophila melanogaster
por: Batista, J.E.S., et al.
Publicado: (2016)

Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX
por: Chen, Yu-Hsin, et al.
Publicado: (2012)

The Bioactive Extract of Pinnigorgia sp. Induces Apoptosis of Hepatic Stellate Cells via ROS-ERK/JNK-Caspase-3 Signaling
por: Kuo, Liang-Mou, et al.
Publicado: (2018)

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
por: Liu, Xin, et al.
Publicado: (2016)

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain
por: Yang, Yang, et al.
Publicado: (2022)

Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα
por: Chen, Po-Jen, et al.
Publicado: (2016)

The activation of p38MAPK and JNK pathways in bovine herpesvirus 1 infected MDBK cells
por: Zhu, Liqian, et al.
Publicado: (2016)

Neurotrophin3 promotes hepatocellular carcinoma apoptosis through the JNK and P38 MAPK pathways
por: Yang, Zhangshuo, et al.
Publicado: (2022)

Marine Natural Product Inhibitors of Neutrophil-Associated Inflammation
por: Chen, Chun-Yu, et al.
Publicado: (2016)

The Chemically Highly Diversified Metabolites from the Red Sea Marine Sponge Spongia sp.
por: Tai, Chi-Jen, et al.
Publicado: (2022)

Nonthermal Plasma Induces Apoptosis in ATC Cells: Involvement of JNK and p38 MAPK-Dependent ROS
por: Lee, Sei Young, et al.
Publicado: (2014)

Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways
por: Wang, Shan, et al.
Publicado: (2018)

Humanin Attenuates NMDA-Induced Excitotoxicity by Inhibiting ROS-dependent JNK/p38 MAPK Pathway
por: Yang, Xiaorong, et al.
Publicado: (2018)

Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
por: Liu, Fu-Chao, et al.
Publicado: (2017)

Glabridin Mediate Caspases Activation and Induces Apoptosis through JNK1/2 and p38 MAPK Pathway in Human Promyelocytic Leukemia Cells
por: Huang, Hsin-Lien, et al.
Publicado: (2014)

Inhibition of cathepsin S confers sensitivity to methyl protodioscin in oral cancer cells via activation of p38 MAPK/JNK signaling pathways
por: Hsieh, Ming-Ju, et al.
Publicado: (2017)

Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation
por: Lee, Tae-Hoon, et al.
Publicado: (2014)

Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways
por: Liu, Haojie, et al.
Publicado: (2017)

High glucose promotes annulus fibrosus cell apoptosis through activating the JNK and p38 MAPK pathways
por: Shan, Lizhen, et al.
Publicado: (2019)

A sestrin-dependent Erk/Jnk/p38 MAPK activation complex inhibits immunity during ageing
por: Lanna, Alessio, et al.
Publicado: (2017)

Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
por: Chen, Xueran, et al.
Publicado: (2020)

Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209
por: Chen, You-Ying, et al.
Publicado: (2022)

IL-8 promotes inflammatory mediators and stimulates activation of p38 MAPK/ERK-NF-κB pathway and reduction of JNK in HNSCC
por: Chan, Leong-Perng, et al.
Publicado: (2017)

Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
por: Pereira, Lorena, et al.
Publicado: (2013)

Immobilization rapidly induces muscle insulin resistance together with the activation of MAPKs (JNK and p38) and impairment of AS160 phosphorylation
por: Kawamoto, Emi, et al.
Publicado: (2016)

Capsaicin mediates caspases activation and induces apoptosis through P38 and JNK MAPK pathways in human renal carcinoma
por: Liu, Tao, et al.
Publicado: (2016)

Identification of p38 MAPK and JNK as new targets for correction of Wilson disease‐causing ATP7B mutants
por: Chesi, Giancarlo, et al.
Publicado: (2016)

p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure
por: Xiao, Yongtao, et al.
Publicado: (2017)

NEFA‐induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non‐alcoholic steatohepatitis
por: Gao, Wenwen, et al.
Publicado: (2018)

Sevoflurane Inhibits Proliferation and Invasion of Human Ovarian Cancer Cells by Regulating JNK and p38 MAPK Signaling Pathway
por: Kang, Kai, et al.
Publicado: (2019)

Sulforaphane reduces intracellular survival of Staphylococcus aureus in macrophages through inhibition of JNK and p38 MAPK-induced inflammation
por: Deramaudt, Therese B., et al.
Publicado: (2020)

Butylphthalide inhibits nerve cell apoptosis in cerebral infarction rats via the JNK/p38 MAPK signaling pathway
por: Bu, Xiangye, et al.
Publicado: (2021)

Neferine induces p38 MAPK/JNK1/2 activation to modulate melanoma proliferation, apoptosis, and oxidative stress
por: Xie, Jun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pnd4jmhi1dbbfbcm7bmvb3g2q8