Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood

Damaged cardiac valves attract blood-borne bacteria, and infective endocarditis is often caused by viridans group streptococci. While such bacteria use multiple adhesins to maintain their normal oral commensal state, recognition of platelet sialoglycans provides an intermediary for binding to damage...

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Detalles Bibliográficos
Autores principales: Deng, Lingquan, Bensing, Barbara A., Thamadilok, Supaporn, Yu, Hai, Lau, Kam, Chen, Xi, Ruhl, Stefan, Sullam, Paul M., Varki, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256463/
https://www.ncbi.nlm.nih.gov/pubmed/25474103
http://dx.doi.org/10.1371/journal.ppat.1004540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256463/
https://www.ncbi.nlm.nih.gov/pubmed/25474103
http://dx.doi.org/10.1371/journal.ppat.1004540

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