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Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood
Damaged cardiac valves attract blood-borne bacteria, and infective endocarditis is often caused by viridans group streptococci. While such bacteria use multiple adhesins to maintain their normal oral commensal state, recognition of platelet sialoglycans provides an intermediary for binding to damage...
Autores principales: | Deng, Lingquan, Bensing, Barbara A., Thamadilok, Supaporn, Yu, Hai, Lau, Kam, Chen, Xi, Ruhl, Stefan, Sullam, Paul M., Varki, Ajit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256463/ https://www.ncbi.nlm.nih.gov/pubmed/25474103 http://dx.doi.org/10.1371/journal.ppat.1004540 |
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