Cargando…

Specific Dysregulation of IFNγ Production by Natural Killer Cells Confers Susceptibility to Viral Infection

Natural Killer (NK) cells contribute to the control of viral infection by directly killing target cells and mediating cytokine release. In C57BL/6 mice, the Ly49H activating NK cell receptor plays a key role in early resistance to mouse cytomegalovirus (MCMV) infection through specific recognition o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fodil, Nassima, Langlais, David, Moussa, Peter, Boivin, Gregory Allan, Di Pietrantonio, Tania, Radovanovic, Irena, Dumaine, Anne, Blanchette, Mathieu, Schurr, Erwin, Gros, Philippe, Vidal, Silvia Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256466/ https://www.ncbi.nlm.nih.gov/pubmed/25473962 http://dx.doi.org/10.1371/journal.ppat.1004511

Ejemplares similares

Genetic dissection of NK cell responses
por: Moussa, Peter, et al.
Publicado: (2013)

Dysregulation in IFN-γ signaling and response: the barricade to tumor immunotherapy
por: Han, Jiashu, et al.
Publicado: (2023)

Regulation of sepsis-induced IFNγ upon natural killer cell or natural killer T cell depletion in vivo
por: Christaki, E, et al.
Publicado: (2012)

Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer
por: Jeyakumar, Thiviya, et al.
Publicado: (2019)

Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
por: Höfle, Johannes, et al.
Publicado: (2022)

The IFN-γ receptor promotes immune dysregulation and disease in STING gain-of-function mice
por: Stinson, W. Alexander, et al.
Publicado: (2022)

Genome-Wide Mouse Mutagenesis Reveals CD45-Mediated T Cell Function as Critical in Protective Immunity to HSV-1
por: Caignard, Grégory, et al.
Publicado: (2013)

The PP2A inhibitor SET regulates natural killer cell IFN-γ production
por: Trotta, Rossana, et al.
Publicado: (2007)

Natural Killer Cells in Afferent Lymph Express an Activated Phenotype and Readily Produce IFN-γ
por: Lund, Hege, et al.
Publicado: (2013)

NK Cell Receptor/H2-D(k)–Dependent Host Resistance to Viral Infection Is Quantitatively Modulated by H2 (q) Inhibitory Signals
por: Fodil-Cornu, Nassima, et al.
Publicado: (2011)

Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral Malaria
por: Berghout, Joanne, et al.
Publicado: (2013)

CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation
por: Kennedy, James M., et al.
Publicado: (2014)

Imbalance in PB IL-17-Secreting and Regulatory Cells in Pars Planitis Is Associated with Dysregulation of IFN-γ-Secreting Cells, Especially in Patients with Clinical Complications
por: Kosmaczewska, Agata, et al.
Publicado: (2020)

Regulation of Anthrax Toxin-Specific Antibody Titers by Natural Killer T Cell-Derived IL-4 and IFNγ
por: Devera, T. Scott, et al.
Publicado: (2011)

An eQTL variant of ZXDC is associated with IFN-γ production following Mycobacterium tuberculosis antigen-specific stimulation
por: Jabot-Hanin, Fabienne, et al.
Publicado: (2017)

Dysregulation of Natural Killer Cells in Obesity
por: O’Shea, Donal, et al.
Publicado: (2019)

Testosterone Increases Susceptibility to Amebic Liver Abscess in Mice and Mediates Inhibition of IFNγ Secretion in Natural Killer T Cells
por: Lotter, Hannelore, et al.
Publicado: (2013)

CCL3 Enhances Antitumor Immune Priming in the Lymph Node via IFNγ with Dependency on Natural Killer Cells
por: Allen, Frederick, et al.
Publicado: (2017)

Interleukin-28B dampens airway inflammation through up-regulation of natural killer cell-derived IFN-γ
por: Yan, Bailing, et al.
Publicado: (2017)

Natural Killer Cell Function Tests by Flowcytometry-Based Cytotoxicity and IFN-γ Production for the Diagnosis of Adult Hemophagocytic Lymphohistiocytosis
por: Lee, Hyeyoung, et al.
Publicado: (2019)

TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-γ Production during Bacterial Infection
por: Kim, Dong Oh, et al.
Publicado: (2020)

Antibody Afucosylation Augments CD16-Mediated Serial Killing and IFNγ Secretion by Human Natural Killer Cells
por: Karampatzakis, Alexandros, et al.
Publicado: (2021)

Cycloartenyl ferulate improves natural killer (NK) cell immunity against cancer by binding to IFNγ receptor 1
por: Li, Mingfeng, et al.
Publicado: (2023)

Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity
por: Krisnawati, Dyah Ika, et al.
Publicado: (2019)

Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
por: He, Tingyan, et al.
Publicado: (2023)

IFNα and IFNγ Impede Marek’s Disease Progression
por: Bertzbach, Luca D., et al.
Publicado: (2019)

Genetic Control of Susceptibility to Infection with Candida albicans in Mice
por: Radovanovic, Irena, et al.
Publicado: (2011)

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
por: Rosain, Jérémie, et al.
Publicado: (2023)

Dysregulation of the IFN-γ-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia
por: Kulling, Paige M., et al.
Publicado: (2018)

Long-term cigarette smoke exposure dysregulates pulmonary T cell response and IFN-γ protection to influenza virus in mouse
por: Wu, Wenxin, et al.
Publicado: (2021)

IFN-γ Mediates the Rejection of Haematopoietic Stem Cells in IFN-γR1-Deficient Hosts
por: Rottman, Martin, et al.
Publicado: (2008)

IFN-γ modulates Ly-49 receptors on NK cells in IFN-γ-induced pregnancy failure
por: Li, Zhong-Yin, et al.
Publicado: (2015)

Natural Killer Cells-Produced IFN-γ Improves Bone Marrow-Derived Hepatocytes Regeneration in Murine Liver Failure Model
por: Li, Lu, et al.
Publicado: (2015)

CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control
por: Veinotte, Linnea, et al.
Publicado: (2016)

Characterization of IFNγ-producing natural killer cells induced by cytomegalovirus reactivation after haploidentical hematopoietic stem cell transplantation
por: Jin, Fengyan, et al.
Publicado: (2016)

Genetic Variability of Human Cytomegalovirus Clinical Isolates Correlates With Altered Expression of Natural Killer Cell-Activating Ligands and IFN-γ
por: Galitska, Ganna, et al.
Publicado: (2021)

Biologic functions of the IFN‐γ receptors
por: Tau, G., et al.
Publicado: (2001)

IFN-γ, should not be ignored in SLE
por: Liu, Wenping, et al.
Publicado: (2022)

Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling
por: Apriamashvili, Georgi, et al.
Publicado: (2022)

Pulmonary IFN-γ Causes Lymphocytic Inflammation and Cough Hypersensitivity by Increasing the Number of IFN-γ-Secreting T Lymphocytes
por: Deng, Zheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hd37rcbamq68p4m04pefc8nptn