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Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics

The fatal neurodegenerative disorders amyotrophic lateral sclerosis and spinal muscular atrophy are, respectively, the most common motoneuron disease and genetic cause of infant death. Various in vitro model systems have been established to investigate motoneuron disease mechanisms, in particular im...

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Detalles Bibliográficos
Autores principales: Hornburg, Daniel, Drepper, Carsten, Butter, Falk, Meissner, Felix, Sendtner, Michael, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256493/
https://www.ncbi.nlm.nih.gov/pubmed/25193168
http://dx.doi.org/10.1074/mcp.M113.037291

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