The Non-receptor Tyrosine Kinase Tec Controls Assembly and Activity of the Noncanonical Caspase-8 Inflammasome

Tec family kinases are intracellular non-receptor tyrosine kinases implicated in numerous functions, including T cell and B cell regulation. However, a role in microbial pathogenesis has not been described. Here, we identified Tec kinase as a novel key mediator of the inflammatory immune response in...

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Detalles Bibliográficos
Autores principales: Zwolanek, Florian, Riedelberger, Michael, Stolz, Valentina, Jenull, Sabrina, Istel, Fabian, Köprülü, Afitap Derya, Ellmeier, Wilfried, Kuchler, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256681/
https://www.ncbi.nlm.nih.gov/pubmed/25474208
http://dx.doi.org/10.1371/journal.ppat.1004525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256681/
https://www.ncbi.nlm.nih.gov/pubmed/25474208
http://dx.doi.org/10.1371/journal.ppat.1004525

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