Molecular Signaling Network Motifs Provide a Mechanistic Basis for Cellular Threshold Responses

Background: Increasingly, there is a move toward using in vitro toxicity testing to assess human health risk due to chemical exposure. As with in vivo toxicity testing, an important question for in vitro results is whether there are thresholds for adverse cellular responses. Empirical evaluations ma...

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Detalles Bibliográficos
Autores principales: Zhang, Qiang, Bhattacharya, Sudin, Conolly, Rory B., Clewell, Harvey J., Kaminski, Norbert E., Andersen, Melvin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NLM-Export 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256703/
https://www.ncbi.nlm.nih.gov/pubmed/25117432
http://dx.doi.org/10.1289/ehp.1408244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256703/
https://www.ncbi.nlm.nih.gov/pubmed/25117432
http://dx.doi.org/10.1289/ehp.1408244

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