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Metastatic gallbladder adenosquamous carcinoma to the skin(†)

Cutaneous metastasis (CM) is an uncommon manifestation of visceral malignancies. Adenosquamous carcinoma of the gallbladder is a rare variation in gallbladder carcinoma (GBC), associated with worse prognosis. We present the case of a 56-year-old woman who presented with an inflamed lump on her abdom...

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Autores principales: Lupinacci, Renato Micelli, Santana, André, Dias, André Roncon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256706/
https://www.ncbi.nlm.nih.gov/pubmed/25480835
http://dx.doi.org/10.1093/jscr/rju130
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author Lupinacci, Renato Micelli
Santana, André
Dias, André Roncon
author_facet Lupinacci, Renato Micelli
Santana, André
Dias, André Roncon
author_sort Lupinacci, Renato Micelli
collection PubMed
description Cutaneous metastasis (CM) is an uncommon manifestation of visceral malignancies. Adenosquamous carcinoma of the gallbladder is a rare variation in gallbladder carcinoma (GBC), associated with worse prognosis. We present the case of a 56-year-old woman who presented with an inflamed lump on her abdominal wall. Computed tomography (CT) revealed a large mass from the gallbladder invading the abdominal wall. She underwent liver resection with regional lymphadenectomy. Pathology analysis revealed a 12-cm pT3N0 GBC. Hospital discharge occurred at post-operative Day 20. She recurred and died 10 months after surgery. Survival after the diagnosis of CM is dismal. The present case was a diagnostic trap. First, the patient's skin lesion presented as a cutaneous abscess and biopsy revealed a squamous cell cancer. A CT scan suggested a continuous mass involving the abdominal wall. CM was only suspected during surgery when no continuity between the tumour and the abdominal wall was identified.
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spelling pubmed-42567062014-12-05 Metastatic gallbladder adenosquamous carcinoma to the skin(†) Lupinacci, Renato Micelli Santana, André Dias, André Roncon J Surg Case Rep Case Reports Cutaneous metastasis (CM) is an uncommon manifestation of visceral malignancies. Adenosquamous carcinoma of the gallbladder is a rare variation in gallbladder carcinoma (GBC), associated with worse prognosis. We present the case of a 56-year-old woman who presented with an inflamed lump on her abdominal wall. Computed tomography (CT) revealed a large mass from the gallbladder invading the abdominal wall. She underwent liver resection with regional lymphadenectomy. Pathology analysis revealed a 12-cm pT3N0 GBC. Hospital discharge occurred at post-operative Day 20. She recurred and died 10 months after surgery. Survival after the diagnosis of CM is dismal. The present case was a diagnostic trap. First, the patient's skin lesion presented as a cutaneous abscess and biopsy revealed a squamous cell cancer. A CT scan suggested a continuous mass involving the abdominal wall. CM was only suspected during surgery when no continuity between the tumour and the abdominal wall was identified. Oxford University Press 2014-12-05 /pmc/articles/PMC4256706/ /pubmed/25480835 http://dx.doi.org/10.1093/jscr/rju130 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2014. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Reports
Lupinacci, Renato Micelli
Santana, André
Dias, André Roncon
Metastatic gallbladder adenosquamous carcinoma to the skin(†)
title Metastatic gallbladder adenosquamous carcinoma to the skin(†)
title_full Metastatic gallbladder adenosquamous carcinoma to the skin(†)
title_fullStr Metastatic gallbladder adenosquamous carcinoma to the skin(†)
title_full_unstemmed Metastatic gallbladder adenosquamous carcinoma to the skin(†)
title_short Metastatic gallbladder adenosquamous carcinoma to the skin(†)
title_sort metastatic gallbladder adenosquamous carcinoma to the skin(†)
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256706/
https://www.ncbi.nlm.nih.gov/pubmed/25480835
http://dx.doi.org/10.1093/jscr/rju130
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AT santanaandre metastaticgallbladderadenosquamouscarcinomatotheskin
AT diasandreroncon metastaticgallbladderadenosquamouscarcinomatotheskin