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Subtoxic levels of hydrogen peroxide induce brain-derived neurotrophic factor expression to protect PC12 cells

BACKGROUND: Oxidative stress is one of the mechanisms underlying pathogenesis in neurodegenerative diseases such as Alzheimer’s disease. Generally, oxidative stress represents cell toxicity; however, we recently found that oxidative stress promotes the expression of growth factor progranulin (PGRN)...

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Detalles Bibliográficos
Autores principales: Ogura, Yurina, Sato, Kazunori, Kawashima, Ken-Ichi, Kobayashi, Nanako, Imura, Sei, Fujino, Kotaro, Kawaguchi, Hideo, Nedachi, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256810/
https://www.ncbi.nlm.nih.gov/pubmed/25424467
http://dx.doi.org/10.1186/1756-0500-7-840