Repair-Related Activation of Hedgehog Signaling in Stromal Cells Promotes Intrahepatic Hypothyroidism

Thyroid hormone (TH) is important for tissue repair because it regulates cellular differentiation. Intrahepatic TH activity is controlled by both serum TH levels and hepatic deiodinases. TH substrate (T(4)) is converted into active hormone (T(3)) by deiodinase 1 (D1) but into inactive hormone (rT(3)...

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Detalles Bibliográficos
Autores principales: Bohinc, Brittany N., Michelotti, Gregory, Xie, Guanhua, Pang, Herbert, Suzuki, Ayako, Guy, Cynthia D., Piercy, Dawn, Kruger, Leandi, Swiderska-Syn, Marzena, Machado, Mariana, Pereira, Thiago, Zavacki, Ann Marie, Abdelmalek, Manal, Diehl, Anna Mae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Thyroid-TRH-TSH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256825/
https://www.ncbi.nlm.nih.gov/pubmed/25121996
http://dx.doi.org/10.1210/en.2014-1302

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