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Deciphering miRNA transcription factor feed-forward loops to identify drug repurposing candidates for cystic fibrosis

BACKGROUND: Cystic fibrosis (CF) is a fatal genetic disorder caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that primarily affects the lungs and the digestive system, and the current drug treatment is mainly able to alleviate symptoms. To improve disease management for...

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Detalles Bibliográficos
Autores principales:	Liu, Zhichao, Borlak, Jürgen, Tong, Weida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256829/ https://www.ncbi.nlm.nih.gov/pubmed/25484921 http://dx.doi.org/10.1186/s13073-014-0094-2

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