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Neutralizing antibodies and fatigue as predictors of low response to interferon-beta treatment in patients with multiple sclerosis
BACKGROUND: The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We con...
Autores principales: | Manceau, Philippe, Latarche, Clotilde, Pittion, Sophie, Edan, Gilles, de Sèze, Jérôme, Massart, Catherine, Debouverie, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256902/ https://www.ncbi.nlm.nih.gov/pubmed/25433670 http://dx.doi.org/10.1186/s12883-014-0215-y |
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