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A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice

BACKGROUND: Genetic variation in the human population is a key determinant of influenza disease severity. A single nucleotide polymorphism in the antiviral gene IFITM3 was linked to outcomes during the 2009 H1N1 pandemic. To identify variant host genes associated with increased virus replication and...

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Detalles Bibliográficos
Autores principales:	Boon, Adrianus CM, Williams, Robert W, Sinasac, David S, Webby, Richard J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256927/ https://www.ncbi.nlm.nih.gov/pubmed/25418976 http://dx.doi.org/10.1186/1471-2164-15-1017

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