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Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene

BACKGROUND: Preserved Ratio Impaired Spirometry (PRISm), defined as a reduced FEV(1) in the setting of a preserved FEV(1)/FVC ratio, is highly prevalent and is associated with increased respiratory symptoms, systemic inflammation, and mortality. Studies investigating quantitative chest tomographic f...

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Detalles Bibliográficos
Autores principales: Wan, Emily S, Castaldi, Peter J, Cho, Michael H, Hokanson, John E, Regan, Elizabeth A, Make, Barry J, Beaty, Terri H, Han, MeiLan K, Curtis, Jeffrey L, Curran-Everett, Douglas, Lynch, David A, DeMeo, Dawn L, Crapo, James D, Silverman, Edwin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256936/
https://www.ncbi.nlm.nih.gov/pubmed/25096860
http://dx.doi.org/10.1186/s12931-014-0089-y