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ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells

Understanding the mechanisms underlying ErbB3 over-expression in breast cancer will facilitate the rational design of therapies to disrupt ErbB2-ErbB3 oncogenic function. While ErbB3 over-expression is frequently observed in breast cancer, the factors mediating its aberrant expression are poorly und...

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Detalles Bibliográficos
Autores principales: Krig, Sheryl R., Miller, Jamie K., Frietze, Seth, Beckett, Laurel A., Neve, Richard M., Farnham, Peggy J., Yaswen, Paul I., Sweeney, Colleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256946/
https://www.ncbi.nlm.nih.gov/pubmed/20661224
http://dx.doi.org/10.1038/onc.2010.289