Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients

The scope of cancer treatment in women of childbearing age has changed in the last decade. Fertility preservation is no longer an afterthought but central to multi-disciplinary cancer treatment planning and should be addressed due to the cytotoxic effects of cancer therapy. However, oncology patient...

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Detalles Bibliográficos
Autores principales: Coyne, Kathryn, Purdy, MacKenzie, O’Leary, Kathleen, Yaklic, Jerome L., Lindheim, Steven R., Appiah, Leslie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256952/
https://www.ncbi.nlm.nih.gov/pubmed/25538933
http://dx.doi.org/10.3389/fpubh.2014.00246
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author Coyne, Kathryn
Purdy, MacKenzie
O’Leary, Kathleen
Yaklic, Jerome L.
Lindheim, Steven R.
Appiah, Leslie A.
author_facet Coyne, Kathryn
Purdy, MacKenzie
O’Leary, Kathleen
Yaklic, Jerome L.
Lindheim, Steven R.
Appiah, Leslie A.
author_sort Coyne, Kathryn
collection PubMed
description The scope of cancer treatment in women of childbearing age has changed in the last decade. Fertility preservation is no longer an afterthought but central to multi-disciplinary cancer treatment planning and should be addressed due to the cytotoxic effects of cancer therapy. However, oncology patients present as a unique treatment challenge as the physician must balance the urgency of fertility preservation with the risks of delaying cancer therapy. Controlled ovarian stimulation (COS) is routinely applied in assisted reproductive technology but can be contraindicated in women with estrogen-receptor-positive tumors. This paper reviews some of the challenges to consider when using COS and newer stimulation protocols to minimize risks and optimize outcomes in oncofertility patients.
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spelling pubmed-42569522014-12-23 Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients Coyne, Kathryn Purdy, MacKenzie O’Leary, Kathleen Yaklic, Jerome L. Lindheim, Steven R. Appiah, Leslie A. Front Public Health Public Health The scope of cancer treatment in women of childbearing age has changed in the last decade. Fertility preservation is no longer an afterthought but central to multi-disciplinary cancer treatment planning and should be addressed due to the cytotoxic effects of cancer therapy. However, oncology patients present as a unique treatment challenge as the physician must balance the urgency of fertility preservation with the risks of delaying cancer therapy. Controlled ovarian stimulation (COS) is routinely applied in assisted reproductive technology but can be contraindicated in women with estrogen-receptor-positive tumors. This paper reviews some of the challenges to consider when using COS and newer stimulation protocols to minimize risks and optimize outcomes in oncofertility patients. Frontiers Media S.A. 2014-12-05 /pmc/articles/PMC4256952/ /pubmed/25538933 http://dx.doi.org/10.3389/fpubh.2014.00246 Text en Copyright © 2014 Coyne, Purdy, O’Leary, Yaklic, Lindheim and Appiah. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Coyne, Kathryn
Purdy, MacKenzie
O’Leary, Kathleen
Yaklic, Jerome L.
Lindheim, Steven R.
Appiah, Leslie A.
Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients
title Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients
title_full Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients
title_fullStr Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients
title_full_unstemmed Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients
title_short Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients
title_sort challenges and considerations in optimizing ovarian stimulation protocols in oncofertility patients
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256952/
https://www.ncbi.nlm.nih.gov/pubmed/25538933
http://dx.doi.org/10.3389/fpubh.2014.00246
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