Scleral melt following Retisert intravitreal fluocinolone implant

Intravitreal fluocinolone acetonide implant (Retisert) has a high potency, a low solubility, and a very short duration of action in the systemic circulation, enabling the steroid pellet to be small and reducing the risk of systemic side effects. Scleral melt has not been reported as a possible compl...

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Autores principales: Georgalas, Ilias, Koutsandrea, Chrysanthi, Papaconstantinou, Dimitrios, Mpouritis, Dimitrios, Petrou, Petros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257017/
https://www.ncbi.nlm.nih.gov/pubmed/25489235
http://dx.doi.org/10.2147/DDDT.S66634
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author Georgalas, Ilias
Koutsandrea, Chrysanthi
Papaconstantinou, Dimitrios
Mpouritis, Dimitrios
Petrou, Petros
author_facet Georgalas, Ilias
Koutsandrea, Chrysanthi
Papaconstantinou, Dimitrios
Mpouritis, Dimitrios
Petrou, Petros
author_sort Georgalas, Ilias
collection PubMed
description Intravitreal fluocinolone acetonide implant (Retisert) has a high potency, a low solubility, and a very short duration of action in the systemic circulation, enabling the steroid pellet to be small and reducing the risk of systemic side effects. Scleral melt has not been reported as a possible complication of Retisert implant. The authors describe the occurrence of scleral melt 18 months after the implantation of fluocinolone acetonide implant in a 42-year-old Caucasian woman. To the authors’ knowledge, this is the first report of this possible complication.
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spelling pubmed-42570172014-12-08 Scleral melt following Retisert intravitreal fluocinolone implant Georgalas, Ilias Koutsandrea, Chrysanthi Papaconstantinou, Dimitrios Mpouritis, Dimitrios Petrou, Petros Drug Des Devel Ther Case Report Intravitreal fluocinolone acetonide implant (Retisert) has a high potency, a low solubility, and a very short duration of action in the systemic circulation, enabling the steroid pellet to be small and reducing the risk of systemic side effects. Scleral melt has not been reported as a possible complication of Retisert implant. The authors describe the occurrence of scleral melt 18 months after the implantation of fluocinolone acetonide implant in a 42-year-old Caucasian woman. To the authors’ knowledge, this is the first report of this possible complication. Dove Medical Press 2014-11-28 /pmc/articles/PMC4257017/ /pubmed/25489235 http://dx.doi.org/10.2147/DDDT.S66634 Text en © 2014 Georgalas et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Georgalas, Ilias
Koutsandrea, Chrysanthi
Papaconstantinou, Dimitrios
Mpouritis, Dimitrios
Petrou, Petros
Scleral melt following Retisert intravitreal fluocinolone implant
title Scleral melt following Retisert intravitreal fluocinolone implant
title_full Scleral melt following Retisert intravitreal fluocinolone implant
title_fullStr Scleral melt following Retisert intravitreal fluocinolone implant
title_full_unstemmed Scleral melt following Retisert intravitreal fluocinolone implant
title_short Scleral melt following Retisert intravitreal fluocinolone implant
title_sort scleral melt following retisert intravitreal fluocinolone implant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257017/
https://www.ncbi.nlm.nih.gov/pubmed/25489235
http://dx.doi.org/10.2147/DDDT.S66634
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