Enhanced local bioavailability of single or compound drugs delivery to the inner ear through application of PLGA nanoparticles via round window administration

In this paper, the potential of poly(d,l-lactide-co-glycolide acid) (PLGA) nanoparticles (NPs) for carrying single or compound drugs traversing the round window membrane (RWM) was examined after the round window (RW) administration of different NPs to guinea pigs. First, coumarin-6 was incorporated...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Hui, Wen, Xingxing, Wen, Lu, Tirelli, Nicola, Zhang, Xiao, Zhang, Yue, Su, Huanpeng, Yang, Fan, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257110/
https://www.ncbi.nlm.nih.gov/pubmed/25489245
http://dx.doi.org/10.2147/IJN.S72555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257110/
https://www.ncbi.nlm.nih.gov/pubmed/25489245
http://dx.doi.org/10.2147/IJN.S72555

Ejemplares similares