Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one

In the title mol­ecule, C(21)H(20)ClF(2)NO(2), the piperidine ring adopts a slightly distorted boat conformation. The two benzene rings form a dihedral angle of 87.43 (1)°. A weak intra­molecular C—H⋯π inter­action is observed. In the crystal, weak C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions c...

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Detalles Bibliográficos
Autores principales: Jothivel, S., Kotoky, Jibon, Kabilan, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257194/
https://www.ncbi.nlm.nih.gov/pubmed/25484669
http://dx.doi.org/10.1107/S1600536814021278
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author Jothivel, S.
Kotoky, Jibon
Kabilan, S.
author_facet Jothivel, S.
Kotoky, Jibon
Kabilan, S.
author_sort Jothivel, S.
collection PubMed
description In the title mol­ecule, C(21)H(20)ClF(2)NO(2), the piperidine ring adopts a slightly distorted boat conformation. The two benzene rings form a dihedral angle of 87.43 (1)°. A weak intra­molecular C—H⋯π inter­action is observed. In the crystal, weak C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions connect the mol­ecules, forming a three-dimensional network.
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spelling pubmed-42571942014-12-05 Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one Jothivel, S. Kotoky, Jibon Kabilan, S. Acta Crystallogr Sect E Struct Rep Online Research Communications In the title mol­ecule, C(21)H(20)ClF(2)NO(2), the piperidine ring adopts a slightly distorted boat conformation. The two benzene rings form a dihedral angle of 87.43 (1)°. A weak intra­molecular C—H⋯π inter­action is observed. In the crystal, weak C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions connect the mol­ecules, forming a three-dimensional network. International Union of Crystallography 2014-09-30 /pmc/articles/PMC4257194/ /pubmed/25484669 http://dx.doi.org/10.1107/S1600536814021278 Text en © Jothivel et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Jothivel, S.
Kotoky, Jibon
Kabilan, S.
Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one
title Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one
title_full Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one
title_fullStr Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one
title_full_unstemmed Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one
title_short Crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one
title_sort crystal structure of 1-(2-chloro­acet­yl)-2,6-bis­(4-fluoro­phen­yl)-3,3-di­methyl­piperidin-4-one
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257194/
https://www.ncbi.nlm.nih.gov/pubmed/25484669
http://dx.doi.org/10.1107/S1600536814021278
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AT kabilans crystalstructureof12chloroacetyl26bis4fluorophenyl33dimethylpiperidin4one

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