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Crystal structure of ammonium 3′-azido-3′-de­oxy­thymidine-5′-amino­carbonyl­phospho­nate hemi­hydrate: an anti-HIV agent

The asymmetric unit of the title compound, NH(4) (+)·C(11)H(14)N(6)O(7)P(−)·0.5H(2)O, contains one 3′-azido-3′-de­oxy­thymidine-5′amino­carbonyl­phospho­nate (ACP–AZT) anion, half of an NH(4) (+) cation lying on a twofold rotation axis and in another position, occupied with equal probabilities of 0....

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Detalles Bibliográficos
Autores principales: Jasko, Maxim V., Gurskaya, Galina V., Kukhanova, Marina K., Bushmarinov, Ivan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257306/
https://www.ncbi.nlm.nih.gov/pubmed/25484756
http://dx.doi.org/10.1107/S1600536814022405