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Crystal structure of (4R,5S)-4-methyl-3-methyl­sulfinyl-5-phenyl-1,3-oxazolidin-2-one

The absolute structure of the chiral asymmetric indole precursor title compound, C(11)H(13)NO(3)S, was confirmed by refinement of the Flack and Hooft parameters and is that expected based on the starting materials for the synthesis. The phenyl group subtends a dihedral angle of 56.40 (5)° with the m...

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Detalles Bibliográficos
Autores principales: Silveira, Gustavo Pozza, da Silva, Vinicius Flores, Oliver, Allen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257383/
https://www.ncbi.nlm.nih.gov/pubmed/25553031
http://dx.doi.org/10.1107/S1600536814024702
Descripción
Sumario:The absolute structure of the chiral asymmetric indole precursor title compound, C(11)H(13)NO(3)S, was confirmed by refinement of the Flack and Hooft parameters and is that expected based on the starting materials for the synthesis. The phenyl group subtends a dihedral angle of 56.40 (5)° with the mean plane of the oxazolidinone ring, which adopts an envelope conformation, with the C atom bearing the methyl group as the flap. In the crystal, no significant directional inter­actions beyond van der Waals contacts are observed.