Cargando…

Insight into the Effect of Inhibitor Resistant S130G Mutant on Physico-Chemical Properties of SHV Type Beta-Lactamase: A Molecular Dynamics Study

Bacterial resistance is a serious threat to human health. The production of β-lactamase, which inactivates β-lactams is most common cause of resistance to the β-lactam antibiotics. The Class A enzymes are most frequently encountered among the four β-lactamases in the clinic isolates. Mutations in cl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baig, Mohd Hassan, Sudhakar, D. Raja, Kalaiarasan, Ponnusamy, Subbarao, Naidu, Wadhawa, Gulshan, Lohani, Mohtashim, Khan, M Kalim A, Khan, Asad U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257546/ https://www.ncbi.nlm.nih.gov/pubmed/25479359 http://dx.doi.org/10.1371/journal.pone.0112456

Ejemplares similares

Screening of inhibitors for S130G inhibitor resistant mutants of TEM type beta-lactamase
por: Baig, Mohd Hassan, et al.
Publicado: (2012)

Molecular docking analysis of new generation cephalosporins interactions with recently known SHV-variants
por: Khan, Asad Ullah, et al.
Publicado: (2011)

Study of a Natural Mutant SHV-Type β-Lactamase, SHV-104, from Klebsiella pneumoniae
por: Ben Achour, Nahed, et al.
Publicado: (2014)

SHV Lactamase Engineering Database: a reconciliation tool for SHV β-lactamases in public databases
por: Thai, Quan K, et al.
Publicado: (2010)

Detection of new SHV-12, SHV-5 and SHV-2a variants of extended spectrum Beta-lactamase in Klebsiella pneumoniae in Egypt
por: Newire, Enas A, et al.
Publicado: (2013)

Molecular docking analysis of aplysin analogs targeting survivin protein
por: Shakeel, Eram, et al.
Publicado: (2017)

A Review of SHV Extended-Spectrum β-Lactamases: Neglected Yet Ubiquitous
por: Liakopoulos, Apostolos, et al.
Publicado: (2016)

Detection of SHV β-lactamases in Gram-negative bacilli using fluorescein-labeled antibodies
por: Hujer, Andrea M, et al.
Publicado: (2009)

In Silico Screening, Genotyping, Molecular Dynamics Simulation and Activity Studies of SNPs in Pyruvate Kinase M2
por: Kalaiarasan, Ponnusamy, et al.
Publicado: (2015)

Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study
por: Krishnan, Nikhil P., et al.
Publicado: (2015)

Molecular interaction analysis of cigarette smoke carcinogens NNK and NNAL with enzymes involved in DNA repair pathways: An in silico approach
por: Jamal, Qazi Mohd Sajid, et al.
Publicado: (2012)

Detection of SHV type Extended-Spectrum B-lactamase and Risk Factors in Pseudomonas aeruginosa Clinical Isolates
por: Bahmani, Nasrin, et al.
Publicado: (2013)

Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds
por: Khan, Saif, et al.
Publicado: (2015)

The Prevalence of TEM and SHV Genes among Extended-Spectrum Beta-Lactamases Producing Escherichia Coli and Klebsiella Pneumoniae
por: Zaniani, Fatemeh Riyahi, et al.
Publicado: (2012)

Prevalence of extended-spectrum beta-lactamases-producing microorganisms in nosocomial patients and molecular characterization of the shv type isolates
por: de Oliveira, Caio Fernando, et al.
Publicado: (2010)

Prevalence of TEM, SHV, and CTX-M Beta-Lactamase genes in the urinary isolates of a tertiary care hospital
por: Bajpai, Trupti, et al.
Publicado: (2017)

Horizontol dissemination of TEM- and SHV-typr beta-lactamase genes-carrying resistance plasmids amongst clonical isolates of Enterobacteriaceae
por: Ozgumus, Osman Birol, et al.
Publicado: (2008)

Structures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation
por: Ke, Wei, et al.
Publicado: (2012)

Multidrug-resistant phenotype and isolation of a Novel SHV- beta-Lactamase variant in a clinical isolate of Enterobacter cloacae
por: Bourouis, Amel, et al.
Publicado: (2015)

Characterization of E. coli Isolates Producing Extended Spectrum Beta-Lactamase SHV-Variants from the Food Chain in Germany
por: Irrgang, Alexandra, et al.
Publicado: (2021)

Enzymatic analysis of the effect of naturally occurring Leu138Pro mutation identified in SHV β-lactamase on hydrolysis of penicillin and ampicillin
por: Rayamajhi, Nabin, et al.
Publicado: (2011)

Antibacterial potential of Forsythia suspensa polysaccharide against resistant Enterobacter cloacae with SHV‐12 extended‐spectrum β‐lactamase (ESBL)
por: Liu, Jun, et al.
Publicado: (2020)

Immunoinformatics Strategy to Develop a Novel Universal Multiple Epitope-Based COVID-19 Vaccine
por: Khamjan, Nizar A., et al.
Publicado: (2023)

Occurrence of SHV, TEM and CTX-M β-Lactamase Genes Among Enteropathogenic Escherichia coli Strains Isolated From Children With Diarrhea
por: Memariani, Mojtaba, et al.
Publicado: (2015)

Spread of TEM, VIM, SHV, and CTX-M β-Lactamases in Imipenem-Resistant Gram-Negative Bacilli Isolated from Egyptian Hospitals
por: Hamdy Mohammed, El sayed, et al.
Publicado: (2016)

Frequency of PER, VEB, SHV, TEM and CTX-M Genes in Resistant Strains of Pseudomonas aeruginosa Producing Extended Spectrum β-Lactamases
por: Bokaeian, Mohmmad, et al.
Publicado: (2014)

Optimization of Extraction Parameters for Enhanced Production of Ovotransferrin from Egg White for Antimicrobial Applications
por: Alshammari, Eyad M. A., et al.
Publicado: (2015)

Detecting a Quasi-stable Imine Species on the Reaction Pathway of SHV-1 β-Lactamase and 6β-(Hydroxymethyl)penicillanic Acid Sulfone
por: Che, Tao, et al.
Publicado: (2014)

Corrigendum to “Spread of TEM, VIM, SHV, and CTX-M β-Lactamases in Imipenem-Resistant Gram-Negative Bacilli Isolated from Egyptian Hospitals”
por: Hamdy Mohammed, El sayed, et al.
Publicado: (2017)

First Outbreak of Multidrug-Resistant Klebsiella pneumoniae Producing both SHV-12-Type Extended-Spectrum β-Lactamase and DHA-1-Type AmpC β-Lactamase at a Korean Hospital
por: Roh, Kyoung Ho, et al.
Publicado: (2008)

Detection of Extended Spectrum B-Lactamases in Urinary Isolates of Klebsiella pneumoniae in Relation to Bla(SHV), Bla(TEM) and Bla(CTX-M) Gene Carriage
por: Eftekhar, F, et al.
Publicado: (2012)

A Multicenter Study of the Clinical and Molecular Epidemiology of TEM- and SHV-type Extended- Spectrum β-Lactamase producing (ESBL) Enterobacteriaceae (Ent) Infections in Children
por: Rispens, Jared R, et al.
Publicado: (2017)

Cefiderocol Resistance in Klebsiella pneumoniae Is Linked to SHV Extended-Spectrum β-Lactamase Activities and Functional Loss of the Outer Membrane Porin OmpK35
por: Moon, Sun Hee, et al.
Publicado: (2023)

Link between MnSOD Ala16Val (rs4880) polymorphism and asthma risk is insignificant from sequential meta-analysis
por: Alhobeira, Hazza A, et al.
Publicado: (2020)

Ratio of βv at scrapers SHV1302 and SLV2105
por: Koziol, H, et al.
Publicado: (1983)

Molecular analysis of bla(SHV), bla(TEM), and bla(CTX-M) in extended-spectrum β-lactamase producing Enterobacteriaceae recovered from fecal specimens of animals
por: Ejaz, Hasan, et al.
Publicado: (2021)

Studies on structure-based sequence alignment and phylogenies of beta-lactamases
por: Salahuddin, Parveen, et al.
Publicado: (2014)

An Immuno-informatics driven Epitope study from the molecular interaction of JEV non-structural (NS) proteins with Ribophorin (RPN)
por: Sayeed, Usman, et al.
Publicado: (2014)

Detection of Escherichia coli and Associated β-Lactamases Genes from Diabetic Foot Ulcers by Multiplex PCR and Molecular Modeling and Docking of SHV-1, TEM-1, and OXA-1 β-Lactamases with Clindamycin and Piperacillin-Tazobactam
por: Shahi, Shailesh K., et al.
Publicado: (2013)

Insilico study on the effect of SARS-CoV-2 RBD hotspot mutants’ interaction with ACE2 to understand the binding affinity and stability
por: Verma, Jyoti, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v3so9kgv5s6ijj59ifommflall