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A Small Molecule Inhibitor of ETV1, YK-4-279, Prevents Prostate Cancer Growth and Metastasis in a Mouse Xenograft Model

BACKGROUND: The erythroblastosis virus E26 transforming sequences (ETS) family of transcription factors consists of a highly conserved group of genes that play important roles in cellular proliferation, differentiation, migration and invasion. Chromosomal translocations fusing ETS factors to promote...

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Detalles Bibliográficos
Autores principales: Rahim, Said, Minas, Tsion, Hong, Sung-Hyeok, Justvig, Sarah, Çelik, Haydar, Kont, Yasemin Saygideger, Han, Jenny, Kallarakal, Abraham T., Kong, Yali, Rudek, Michelle A., Brown, Milton L., Kallakury, Bhaskar, Toretsky, Jeffrey A., Üren, Aykut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257561/
https://www.ncbi.nlm.nih.gov/pubmed/25479232
http://dx.doi.org/10.1371/journal.pone.0114260