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A Small Molecule Inhibitor of ETV1, YK-4-279, Prevents Prostate Cancer Growth and Metastasis in a Mouse Xenograft Model
BACKGROUND: The erythroblastosis virus E26 transforming sequences (ETS) family of transcription factors consists of a highly conserved group of genes that play important roles in cellular proliferation, differentiation, migration and invasion. Chromosomal translocations fusing ETS factors to promote...
Autores principales: | Rahim, Said, Minas, Tsion, Hong, Sung-Hyeok, Justvig, Sarah, Çelik, Haydar, Kont, Yasemin Saygideger, Han, Jenny, Kallarakal, Abraham T., Kong, Yali, Rudek, Michelle A., Brown, Milton L., Kallakury, Bhaskar, Toretsky, Jeffrey A., Üren, Aykut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257561/ https://www.ncbi.nlm.nih.gov/pubmed/25479232 http://dx.doi.org/10.1371/journal.pone.0114260 |
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