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Hyperosmolarity Invokes Distinct Anti-Inflammatory Mechanisms in Pulmonary Epithelial Cells: Evidence from Signaling and Transcription Layers

Hypertonic saline (HTS) has been used intravenously to reduce organ dysfunction following injury and as an inhaled therapy for cystic fibrosis lung disease. The role and mechanism of HTS inhibition was explored in the TNFα and IL-1β stimulation of pulmonary epithelial cells. Hyperosmolar (HOsm) medi...

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Detalles Bibliográficos
Autores principales: Wright, Franklin L., Gamboni, Fabia, Moore, Ernest E., Nydam, Trevor L., Mitra, Sanchayita, Silliman, Christopher C., Banerjee, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257597/
https://www.ncbi.nlm.nih.gov/pubmed/25479425
http://dx.doi.org/10.1371/journal.pone.0114129