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Hyperosmolarity Invokes Distinct Anti-Inflammatory Mechanisms in Pulmonary Epithelial Cells: Evidence from Signaling and Transcription Layers
Hypertonic saline (HTS) has been used intravenously to reduce organ dysfunction following injury and as an inhaled therapy for cystic fibrosis lung disease. The role and mechanism of HTS inhibition was explored in the TNFα and IL-1β stimulation of pulmonary epithelial cells. Hyperosmolar (HOsm) medi...
Autores principales: | Wright, Franklin L., Gamboni, Fabia, Moore, Ernest E., Nydam, Trevor L., Mitra, Sanchayita, Silliman, Christopher C., Banerjee, Anirban |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257597/ https://www.ncbi.nlm.nih.gov/pubmed/25479425 http://dx.doi.org/10.1371/journal.pone.0114129 |
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