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The Eukaryotic Elongation Factor 1A Is Critical for Genome Replication of the Paramyxovirus Respiratory Syncytial Virus
The eukaryotic translation factor eEF1A assists replication of many RNA viruses by various mechanisms. Here we show that down-regulation of eEF1A restricts the expression of viral genomic RNA and the release of infectious virus, demonstrating a biological requirement for eEF1A in the respiratory syn...
Autores principales: | Wei, Ting, Li, Dongsheng, Marcial, Daneth, Khan, Moshin, Lin, Min-Hsuan, Snape, Natale, Ghildyal, Reena, Harrich, David, Spann, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257679/ https://www.ncbi.nlm.nih.gov/pubmed/25479059 http://dx.doi.org/10.1371/journal.pone.0114447 |
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