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Extended Ultrastructural Characterization of Chordoma Cells: The Link to New Therapeutic Options

Chordomas are rare bone tumors, developed from the notochord and largely resistant to chemotherapy. A special feature of this tumor is the heterogeneity of its cells. By combining high pressure freezing (HPF) with electron tomography we were able to illustrate the connections within the cells, the c...

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Detalles Bibliográficos
Autores principales:	Kolb, Dagmar, Pritz, Elisabeth, Steinecker-Frohnwieser, Bibiane, Lohberger, Birgit, Deutsch, Alexander, Kroneis, Thomas, El-Heliebi, Amin, Dohr, Gottfried, Meditz, Katharina, Wagner, Karin, Koefeler, Harald, Leitinger, Gerd, Leithner, Andreas, Liegl-Atzwanger, Bernadette, Zweytick, Dagmar, Rinner, Beate
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257693/ https://www.ncbi.nlm.nih.gov/pubmed/25479055 http://dx.doi.org/10.1371/journal.pone.0114251

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