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MHC-Ig induces memory T cell formation in vivo and inhibits tumour growth

Induction of a T cell mediated immune response is critical for the eradication of viral infections and tumours. Soluble peptide-loaded major histocompatibility complex-Ig ((pep−)MHC-Ig) have been shown to bind their cognate ligands, T cell receptor, with high affinity, and are successfully used to v...

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Detalles Bibliográficos
Autores principales: Schütz, Christian, Zoso, Alessia, Peng, Shiwen, Bennett, Jonathon D, Schneck, Jonathan P, Oelke, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257763/
https://www.ncbi.nlm.nih.gov/pubmed/25505552
http://dx.doi.org/10.1002/iid3.35