Cargando…

Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand

Shiga toxin-producing Escherichia coli (STEC) O157:H7 is a zoonotic pathogen of public health concern worldwide. To compare the local and large-scale geographic distributions of genotypes of STEC O157:H7 isolates obtained from various bovine and human sources during 2008–2011, we used pulsed-field g...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaros, Patricia, Cookson, Adrian L., Campbell, Donald M., Duncan, Gail E., Prattley, Deborah, Carter, Philip, Besser, Thomas E., Shringi, Smriti, Hathaway, Steve, Marshall, Jonathan C., French, Nigel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257794/
https://www.ncbi.nlm.nih.gov/pubmed/25568924
http://dx.doi.org/10.3201/eid2012.140281
_version_ 1782347806750539776
author Jaros, Patricia
Cookson, Adrian L.
Campbell, Donald M.
Duncan, Gail E.
Prattley, Deborah
Carter, Philip
Besser, Thomas E.
Shringi, Smriti
Hathaway, Steve
Marshall, Jonathan C.
French, Nigel P.
author_facet Jaros, Patricia
Cookson, Adrian L.
Campbell, Donald M.
Duncan, Gail E.
Prattley, Deborah
Carter, Philip
Besser, Thomas E.
Shringi, Smriti
Hathaway, Steve
Marshall, Jonathan C.
French, Nigel P.
author_sort Jaros, Patricia
collection PubMed
description Shiga toxin-producing Escherichia coli (STEC) O157:H7 is a zoonotic pathogen of public health concern worldwide. To compare the local and large-scale geographic distributions of genotypes of STEC O157:H7 isolates obtained from various bovine and human sources during 2008–2011, we used pulsed-field gel electrophoresis and Shiga toxin–encoding bacteriophage insertion (SBI) typing. Using multivariate methods, we compared isolates from the North and South Islands of New Zealand with isolates from Australia and the United States. The STEC O157:H7 population structure differed substantially between the 2 islands and showed evidence of finer scale spatial structuring, which is consistent with highly localized transmission rather than disseminated foodborne outbreaks. The distribution of SBI types differed markedly among isolates from New Zealand, Australia, and the United States. Our findings also provide evidence for the historic introduction into New Zealand of a subset of globally circulating STEC O157:H7 strains that have continued to evolve and be transmitted locally between cattle and humans.
format Online
Article
Text
id pubmed-4257794
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-42577942014-12-16 Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand Jaros, Patricia Cookson, Adrian L. Campbell, Donald M. Duncan, Gail E. Prattley, Deborah Carter, Philip Besser, Thomas E. Shringi, Smriti Hathaway, Steve Marshall, Jonathan C. French, Nigel P. Emerg Infect Dis Research Shiga toxin-producing Escherichia coli (STEC) O157:H7 is a zoonotic pathogen of public health concern worldwide. To compare the local and large-scale geographic distributions of genotypes of STEC O157:H7 isolates obtained from various bovine and human sources during 2008–2011, we used pulsed-field gel electrophoresis and Shiga toxin–encoding bacteriophage insertion (SBI) typing. Using multivariate methods, we compared isolates from the North and South Islands of New Zealand with isolates from Australia and the United States. The STEC O157:H7 population structure differed substantially between the 2 islands and showed evidence of finer scale spatial structuring, which is consistent with highly localized transmission rather than disseminated foodborne outbreaks. The distribution of SBI types differed markedly among isolates from New Zealand, Australia, and the United States. Our findings also provide evidence for the historic introduction into New Zealand of a subset of globally circulating STEC O157:H7 strains that have continued to evolve and be transmitted locally between cattle and humans. Centers for Disease Control and Prevention 2014-12 /pmc/articles/PMC4257794/ /pubmed/25568924 http://dx.doi.org/10.3201/eid2012.140281 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Jaros, Patricia
Cookson, Adrian L.
Campbell, Donald M.
Duncan, Gail E.
Prattley, Deborah
Carter, Philip
Besser, Thomas E.
Shringi, Smriti
Hathaway, Steve
Marshall, Jonathan C.
French, Nigel P.
Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand
title Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand
title_full Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand
title_fullStr Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand
title_full_unstemmed Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand
title_short Geographic Divergence of Bovine and Human Shiga Toxin–Producing Escherichia coli O157:H7 Genotypes, New Zealand
title_sort geographic divergence of bovine and human shiga toxin–producing escherichia coli o157:h7 genotypes, new zealand
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257794/
https://www.ncbi.nlm.nih.gov/pubmed/25568924
http://dx.doi.org/10.3201/eid2012.140281
work_keys_str_mv AT jarospatricia geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT cooksonadrianl geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT campbelldonaldm geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT duncangaile geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT prattleydeborah geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT carterphilip geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT besserthomase geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT shringismriti geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT hathawaysteve geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT marshalljonathanc geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand
AT frenchnigelp geographicdivergenceofbovineandhumanshigatoxinproducingescherichiacolio157h7genotypesnewzealand