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Two Anaplasma phagocytophilum Strains in Ixodes scapularis Ticks, Canada

We developed PCR-based assays to distinguish a human pathogenic strain of Anaplasma phagocytophilum, Ap-ha, from Ap-variant 1, a strain not associated with human infection. The assays were validated on A. phagocytophilum-infected blacklegged ticks (Ixodes scapularis) collected in Canada. The relativ...

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Detalles Bibliográficos
Autores principales: Krakowetz, Chantel N., Dibernardo, Antonia, Lindsay, L. Robbin, Chilton, Neil B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257797/
https://www.ncbi.nlm.nih.gov/pubmed/25417645
http://dx.doi.org/10.3201/eid2012.140172
Descripción
Sumario:We developed PCR-based assays to distinguish a human pathogenic strain of Anaplasma phagocytophilum, Ap-ha, from Ap-variant 1, a strain not associated with human infection. The assays were validated on A. phagocytophilum-infected blacklegged ticks (Ixodes scapularis) collected in Canada. The relative prevalence of these 2 strains in I. scapularis ticks differed among geographic regions.