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Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types
Major histocompatibility class II (MHC-II) expression is critical for immune responses and is controlled by the MHC-II transactivator CIITA. CIITA is primarily regulated at the transcriptional level and is expressed from three main promoters with myeloid, lymphoid, and IFN-γ treated non-hematopoieti...
Autores principales: | Lohsen, Sarah, Majumder, Parimal, Scharer, Christopher D., Barwick, Benjamin G., Austin, James W., Zinzow-Kramer, Wendy M., Boss, Jeremy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257854/ https://www.ncbi.nlm.nih.gov/pubmed/25101797 http://dx.doi.org/10.1038/gene.2014.49 |
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