Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia

Many neurodegenerative diseases, such as frontotemporal dementia (FTD), are associated with behavioral deficits, but the anatomical and molecular bases remain poorly understood. Here we show that forebrain-specific expression of FTD-associated mutant CHMP2B causes several age-dependent neurodegenera...

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Detalles Bibliográficos
Autores principales: Gascon, Eduardo, Lynch, Kelleen, Ruan, Hongyu, Almeida, Sandra, Verheyden, Jamie, Seeley, William W., Dickson, Dennis W., Petrucelli, Leonard, Sun, Danqiong, Jiao, Jian, Zhou, Hongru, Jakovcevski, Mira, Akbarian, Schahram, Yao, Wei-Dong, Gao, Fen-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257887/
https://www.ncbi.nlm.nih.gov/pubmed/25401692
http://dx.doi.org/10.1038/nm.3717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257887/
https://www.ncbi.nlm.nih.gov/pubmed/25401692
http://dx.doi.org/10.1038/nm.3717

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