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β-catenin mediates behavioral resilience through Dicer1/microRNA regulation
β-catenin is a multi-functional protein that plays an important role in the mature central nervous system; its dysfunction has been implicated in several neuropsychiatric disorders, including depression. Here we show that β-catenin mediates pro-resilient and anxiolytic effects in mice in the nucleus...
Autores principales: | Dias, Caroline, Feng, Jian, Sun, Haosheng, Shao, Ning-yi, Mazei-Robison, Michelle S., Damez-Werno, Diane, Scobie, Kimberly, Bagot, Rosemary, LaBonte, Benoit, Ribeiro, Efrain, Liu, XiaoChuan, Kennedy, Pamela, Vialou, Vincent, Ferguson, Deveroux, Pena, Catherine, Calipari, Erin, Koo, Jawook, Mouzon, Ezekiell, Ghose, Subruto, Tamminga, Carol, Neve, Rachael, Shen, Li, Nestler, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257892/ https://www.ncbi.nlm.nih.gov/pubmed/25383518 http://dx.doi.org/10.1038/nature13976 |
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