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Transcriptional regulation of autophagy by an FXR/CREB axis
Lysosomal degradation of cytoplasmic components by autophagy is essential for cellular survival and homeostasis under nutrient-deprived conditions(1–4). Acute regulation of autophagy by nutrient-sensing kinases is well defined(3, 5–7), but longer-term transcriptional regulation is relatively unknown...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257899/ https://www.ncbi.nlm.nih.gov/pubmed/25383523 http://dx.doi.org/10.1038/nature13949 |